Degenerative myelopathy - Page 6

II didn't read any of the rest of your post. No point in reading it. The second sentence was enough to disregard the rest.:-)       
 

 No point in reading it?  How can it ever hurt to read and consider opposing opinions on DM and the DNA test (or anything else for that matter)?

Blitzen, it was the insulting that turned me off from reading past the second sentence. Besides, over the many years this topic has been hashed over, there has been nothing new or revealing that makes it worth my time to wade through a post that starts out insulting a person who dares to point out unpopular facts.
So, yeah, no point in reading bs.

Here forever so lucky is supporting the reason offa does not accept 'clear' based on grandparents 'clear' test results because of mutation ( BTW, forever, that's not a scary word, so relax)....

Quote from forever so Lucky's post; " Since DM is such a devastating disease, you don't want to miss one of those spontaneous mutations."

So where's the 'nonsense' ?

Mutation is uncontrollable so the disease will not be eliminated by DNA testing...it sounds good though, when getting people to get onboard. Sod1 is obviously not the cause of DM. Forever so lucky even says so.

Well, if members would stop reading posts to this forum because they found the content insulting,they'd be skipping over most of mine and yours, Joan.

blitzen, speak for yourself, thank you. I was speaking to the topic, when lucky made it a personal insult because they evidently thought they disagreed with me. But really lucky forever posted information supporting what I said. Again, where's the 'nonsense' in what I said?

Besides, blitzen, what *members* skip or not has nothing to do with why I chose not to read past the second sentence of lucky forever's post. What 'members' skip or not, also has nothing to do with this thread.

OK, have a good day.

Wow - that takes some suuuuuper special twisted logic to make it sound like I agree with you, Joan.

Guess I have to clarify.

I agree with peer-reviewed, published literature that shows the SOD1 mutation (118G>A) causes degenerative myelopathy in a subset of At Risk (AA) German Shepherd Dogs.

I believe that based on the low numbers of necropsy-confirmed false negatives, the test is specific above the industry and regulatory standards for diagnostic tests.

I have tested both of my GSDs with the OFA test and will continue to test any future GSDs.  They're both listed in the database despite our BYB, spayed female testing as Carrier.  I support the OFA's SOD1 genotyping assay.

I believe that SOD1 testing should be a standard screening test like hips and elbows and results should be taken into consideration when making breeding decisions.

I agree with OFA's decision to use "Clear by Parentage" for a single generation after tested parents due to the struck-by-lightning-frequency spontaneous mutation.  Not worth the risk of a freak At Risk event leading to 10+ years of fertility in a male and having the gene flung far and wide before clinical DM presentation.

(PS - Blitzen, you were doing fine...  Just wanted to throw my support behind you to counteract any seeds of doubt that might have gotten planted due to conviction rather than knowledge.)

 

Forever lucky, I didn't say you agree with me. But I have the same information you have and you inadvertantly supported that with your posts. You try too hard to word the facts to your favor but it still comes out basically the same as what I said. Btw,you tested two dogs? Well I've tested a dozen. And I'm sure offa will be relieved to know you 'agree' with them on their proto call. I mentioned the testing of clear parentage offspring to show you that 'mutation' actually is a factor, and not just a 'scary word' as you claimed. So now you pointed out that you understand what mutation is..that's good. Your 'conviction' shows you have no tolerance for any persons who you think don't share your opinion. That's what wars are made of.........

Are your tested dogs on the OFA database, Joan?